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Home2 Suites by Hilton Rochester Mayo Clinic Area is ideally located off of U.S. 52 and U.S. 63, within minutes of the world famous Mayo Clinic, Saint Marys Hospital, Rochester International Airport, Plummer House, Mayo Civic Center, and Graham Arena. Here to play? Our hotel is connected to the scenic Zumbro River Trail system, offering access to 80 miles of paved biking and walking trails; and our staff can recommend the area's best spots for biking, golfing, fishing and hiking. We’re also just steps away from the Apache Mall, south-eastern Minnesota’s premier shopping destination. Enjoy the convenience of our neighboring restaurants which include Panera Bread and Hot Chip Burger Bar within walking distance to our property. Whether you're here for a short-term or extended stay we're perfectly suited to accommodate your needs.

Rates above are for one room, one night. Unless otherwise stated, rates do not include all taxes and fees.

What are Loyalty Member Rates?

Room Key gives you access to low Loyalty Member Rates for more than 60 of the world’s largest hotel chains all in one place. Loyalty Rates are rates typically reserved for members of the hotel’s loyalty program available mainly on the hotel’s own website. Now Room Key is the only travel site where customers can shop and compare Loyalty Rates across so many hotel chains all in one place.

To book a Loyalty Rate, simply enroll in the hotel’s loyalty program (it’s free) and provide your membership number when booking. You’ll instantly qualify for the Loyalty Rate and get all of the loyalty member benefits as well. There are no hidden fees or paid memberships required.